The hypothalamus of the brain detects a drop in blood temperature.
The hypothalamus stimulates the pituitary to secrete TSH (thyroid-stimulating hormone).
This hormone stimulates the thyroid to increase its secretion of thyroxine.
The higher concentration of thyroxine increases metabolism and heat production increases.
The blood is warmed back to normal temperature.
Hypothalamus detecting raised blood temperature and reduces its stimulation of the pituitary.
High thyroxine levels inhibiting the release of TSH from the pituitary.
The increased level of thyroxine leads to the limitation or reduction of its secretion.
Body’s metabolism slows down as a result of less thyroxin. The body’s temperature goes down.

Diabetes results from inadequate levels of insulin. Type I diabetes is characterized by inadequate levels of insulin secretion, often due to a genetic cause. Type II usually develops in adults from both genetic and environmental causes. Loss of response of targets to insulin rather than lack of insulin causes this type of diabetes. Diabetes causes impairment in the functioning of the eyes, circulatory system, nervous system, and failure of the kidneys. Diabetes is the second leading cause of blindness in the US. Treatments involve daily injections of insulin, monitoring of blood glucose levels and a controlled diet.