Intralesional steroid injections for psoriasis

Intralesional injection of a steroid is done as an out-patient procedure, with no special preparation involved. You should tell the doctor if you have any allergies or problems with your general health. Although the area to be treated can be numbed with a local anaesthetic, this is not normally necessary; the discomfort associated with the steroid injection is very similar to that caused by an injection of local anaesthetic. Depending on the size of the area to be treated, a number of injections may be required. Your doctor will probably place a small dressing over the injected site, and this can be removed after a few hours. Depending on the condition being treated, you may be offered further treatment sessions, at least several weeks apart.

Alphatrex:
- Protect from freezing
- Protect from light
- Store at 77 degrees F; excursions permitted to 59-86 degrees F
Beta 1 Kit:
- Store at controlled room temperature (between 68 and 77 degrees F)
Beta Derm :
- Store at room temperature (between 59 to 86 degrees F)
Betanate :
- Store at room temperature (between 59 to 86 degrees F)
Betatrex:
- Store at room temperature (between 59 to 86 degrees F)
Beta-Val:
- Store at room temperature (between 59 to 86 degrees F)
Celestone:
- Protect from light
- Store at 77 degrees F; excursions permitted to 59-86 degrees F
Del-Beta :
- Protect from freezing
- Protect from light
- Store at 77 degrees F; excursions permitted to 59-86 degrees F
Diprolene:
- Store between 36 to 77 degrees F
Diprolene AF:
- Store between 36 to 86 degrees F
Diprosone:
- Protect from freezing
- Protect from light
- Store at 77 degrees F; excursions permitted to 59-86 degrees F
Luxiq Foam:
- Do Not Store at Temperatures Above 120 degrees F (49 degrees C)
- Flammable, keep away from heat and flame
- Store at controlled room temperature (between 68 and 77 degrees F)
Maxivate:
- Protect from freezing
- Protect from light
- Store at 77 degrees F; excursions permitted to 59-86 degrees F
RRB Pak:
- Store between 36 to 86 degrees F
Sernivo:
- Discard unused product 28 days after opening the bottle
- Store between 68 to 77 degrees F, excursions permitted 59 to 86 degrees F
Valisone:
- Store at room temperature (between 59 to 86 degrees F)

For acne cysts on the face, it is safer to use 1 to 2 mg/mL to make sure that atrophy does not occur. On the trunk consider using 2 to  mg/mL of triamcinolone. Enough suspension should be injected to see and feel the cyst become distended, but no more than  mL is needed for any one cyst. One injection site per acne cyst should be adequate. If the cyst is large and soft, do not inject more volume because that can lead to atrophy. If there is a lot of purulent material inside the cyst, a quick incision and drainage (with lidocaine and a No. 11 scalpel) before injecting the steroid may be helpful.

Oral cyclosporine was effective in the DEBR model for alopecia areata. All rats had a full pelage by 5 weeks of treatment with 10 mg/kg/d, 5 d/wk for 7 weeks. Studies in humans also have proven efficacy with doses of 6 mg/kg/d for 3 months in 6 patients. All patients experienced regrowth, and cosmetically acceptable regrowth was seen in 3 of 6 patients. Unfortunately, all patients relapsed within 3 months of discontinuation of cyclosporine. No evidence indicates that CsA can prevent hair loss during an active episode because reports have described patients taking CsA who developed alopecia areata while they were under treatment for unrelated conditions.

Intralesional steroid injections for psoriasis

intralesional steroid injections for psoriasis

Oral cyclosporine was effective in the DEBR model for alopecia areata. All rats had a full pelage by 5 weeks of treatment with 10 mg/kg/d, 5 d/wk for 7 weeks. Studies in humans also have proven efficacy with doses of 6 mg/kg/d for 3 months in 6 patients. All patients experienced regrowth, and cosmetically acceptable regrowth was seen in 3 of 6 patients. Unfortunately, all patients relapsed within 3 months of discontinuation of cyclosporine. No evidence indicates that CsA can prevent hair loss during an active episode because reports have described patients taking CsA who developed alopecia areata while they were under treatment for unrelated conditions.

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