Williams syndrome is a genetic disorder characterized by the deletion of genetic material approximately Mb from the POR gene (POR). Cells with this genetic deletion show reduced transcription of POR, it seems, due to the loss of a cis-regulatory element that alters expression of this gene.  Some persons with Williams syndrome show characteristics of POR deficiency, including radioulnar synostosis and other skeletal abnormalities.  Cases of mild impairment of cortisol and androgen synthesis have been noted,  however, despite the fact that deficient POR impairs androgen synthesis, patients with Williams syndrome often show increased androgen levels.  A similar increase in testosterone has been observed in a mouse model that has globally decreased POR expression. 
If all continues to go well on Npp I'll be switching to good ole Deca soon. Less pinning less hassle. Was planning to hold out for some Balkan labs 'incoming' shortly from 101 - but I may now just stick with SIS labs. They've seen me right so far so may win my loyalty going forward if their Tri- Deca is as good as this Npp.
Just one suggestion - SIS should identify the actual carrier oil used. While I had no problems many folks have allergy issues. Helps everyone make an informed, healthy choice.
Other than this - overall a very positive experience with both 101 and SIS labs.
I'd have no hesitation recommending both to anyone considering using them.
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