Intervertebral disk – a structure that separates the vertebrae. It serves to absorb the movements of the vertebrae. Intervertebral disc consists of the so-called pulpal core special jelly mass and envelops the fibrous ring, which consists of fibers. Fibrous ring partially fixed to the adjacent vertebral bodies, and partially – to the adjacent intervertebral ligaments. Some parts of the ring are “free” and there may be some stretching of it. Excess load on the fibrous ring leads to the fact that the nucleus breaks pulpal core break fibrous ring at a greater or lesser extent. This leads to the formation of disk herniation .
Depending on the number and character of their functional groups, steroid molecules may show diverse reactivities. Moreover, the reactivity of a functional group varies according to its location within the molecule (for example, esters are formed readily by 3-OH groups but only with difficulty by the 11β-OH group). An important property of steroids is polarity —., their solubility in oxygen-containing solvents (., water and alcohols ) rather than hydrocarbon solvents (., hexane and benzene ). Hydroxyl, ketonic, or ionizable (capable of dissociating to form electrically charged particles) groups in a steroid molecule increase its polarity to an extent that is strongly influenced by the spatial arrangement of the atoms within the molecule.
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