So just how effective is Activate Xtreme™? We conducted an in-house pilot study involving a small group of four participants who used Activate Xtreme™ for four weeks with no other dietary supplements. They followed their usual well-regimented diet and training program and had blood work taken by professional doctors which was then assayed by independent laboratories. On average, tester’s TOTAL testosterone increased by 105% , and their FREE testosterone jumped 136%!! Estrogen was controlled perfectly, with no increases and an average decline of %.*
To execute the prediction, PASS requires a knowledge base about structure-activity relationships for compounds with known biological activities. This is provided by SAR Base, containing the analysis results obtained with an in-house training set of more than 250,000 compounds with known biological activities. This training set is continuously curated and expanded. SAR Base can also be replaced by an exclusive knowledge base, which can be created using in-house data. The knowledge base together with the user-defined constraints of biological activities of interest and relevant parameters provides PASS the starting point for the computational prediction.
HSD11B1 (Hydroxysteroid 11-Beta Dehydrogenase 1) is a Protein Coding gene. Diseases associated with HSD11B1 include Cortisone Reductase Deficiency 2 and Hyperandrogenism Due To Cortisone Reductase Deficiency . Among its related pathways are Metabolism and Steroid hormone biosynthesis . Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and 11-beta-hydroxysteroid dehydrogenase (NADP+) activity . An important paralog of this gene is HSD11B1L .